Association of apolipoprotein B gene variants with plasma apoB and low density lipoprotein (LDL) cholesterol levels.

doi:10.1007/BF00215683

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Article

Association of apolipoprotein B gene variants with plasma apoB and low density lipoprotein (LDL) cholesterol levels.

Human genetics - 1 Feb 1992

Deeb S S, Failor R A, Brown B G, Brunzell J D, Albers J J, Motulsky A G, Wijsman E

Abstract excerpt

The contribution of the variants of the apolipoprotein (apo) B locus to the total variance in plasma apoB and cholesterol levels was examined in four independent populations, two that were composed of normal controls (n = 77 and 85) and two with coronary heart disease (n = 115 and 159). A correlation between genotype at the apoB-XbaI locus and apoB levels was observed. The effects of the (+; presence of...

Topics

Adult
Alleles
Amino Acid Sequence
Apolipoproteins B
Base Sequence
Cholesterol
Cholesterol, LDL
Coronary Disease
Female
Gene Frequency
Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Humans

Male

Molecular Sequence Data

Oligodeoxyribonucleotides

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 1346774
DOI: 10.1007/BF00215683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1346774-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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