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Article

DNA polymorphism studies. Approaches to elucidating multifactorial ischaemic heart disease: the apo B gene as an example.

Annals of medicine - 1 Oct 1992

Humphries S E, Dunning A, Xu C F, Peacock R, Talmud P, Hamsten A

Abstract excerpt

It is well established that elevated plasma levels of low-density lipoprotein (LDL) particles are a risk factor for ischaemic heart disease with the distribution in LDL levels seen in the general population being the result of interaction between environmental factors, such as dietary fat intake, and genetic variation that is present in different individuals. One of the candidate genes where such variation is...

Topics

Alleles
Apolipoproteins B
Cholesterol
Coronary Disease
DNA
Epitopes
Genes
Genotype
Humans
Hyperlipidemias
Lipids
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Risk Factors

Source

Identifiers

PMID: 1384565
DOI: 10.3109/07853899209147836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1384565-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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