Article
Genetic variation of apolipoprotein B can produce both low and high levels of apoB-containing lipoproteins in plasma.
The Canadian journal of cardiology - 1 Oct 1995
Schonfeld G
Abstract excerpt
The polymorphic markers of the apolipoprotein B (apoB) gene include restriction fragment length polymorphisms (RFLPs) scattered along the length of the gene, an insertion/deletion (I/D) polymorphism at the 5' and variable numbers of tandem repeats (VNTRs) at the 3' untranslated ends. The Xbal and I/D polymorphisms which do not affect apoB structure, produce modest effects on fasting and postprandial lipids and on...
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