Article
Genetic variation in the amino-terminal part of apolipoprotein B: studies in hyperlipidemic patients.
Atherosclerosis - 1 Jun 1998
Ilmonen M, Knudsen P, Taskinen M R, Tikkanen M J
Abstract excerpt
Hypertriglyceridemia is a heterogeneous lipid disorder often running in families. Variation in the apolipoprotein B (apo B) gene has been associated with serum triglyceride levels. Recently, a role of the amino-terminal end of apo B in binding with lipoprotein lipase (LPL) has been suggested. We screened the 5' end of the apo B gene in 76 Finnish severely hypertriglyceridemic (> 6 mmol/l) patients, using a...
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