Article
Screening of the 3' two-thirds of the coding area of the apo B gene in Finnish hypercholesterolemic patients report of six new genetic variants.
Atherosclerosis - 10 Feb 1997
Ilmonen M, Ebeling T, Viikari J, Ojala J P, Tikkanen M J
Abstract excerpt
Hypercholesterolemia clustering in families not explained by either low density lipoprotein (LDL)-receptor mutations producing familial hypercholesterolemia (FH), or the apolipoprotein B (apo B) Arg3500-->Gln mutation with familial defective apo B (FDB), is common in the Finnish population. In se...
Topics
- Apolipoproteins B
- Base Sequence
- Exons
- Finland
- Gene Frequency
- Genetic Code
- Genetic Testing
- Genetic Variation
- Haplotypes
- Humans
- Hypercholesterolemia
- Lipids
- Pedigree
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational