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Metoprolol alpha-hydroxylation capacity in 96 Chinese Han volunteers.

Zhongguo yao li xue bao = Acta pharmacologica Sinica - 1 Jul 1995

Tu Z G, Zhao L L

Abstract excerpt

AIM: To study the ability of oxidizing metoprolol (Met) to form alpha-hydroxymetoprolol (HM) in Chinese in vivo and in vitro. METHODS: An ion-pair reverse phase high performance liquid chromatography was used. RESULTS: In vivo study, the 8-h urinary recoveries of Met and HM after po Met tartrate 100 mg were tested in 96 unrelated healthy Chinese Han volunteers, and the capacity of Met alpha-hydroxylation...

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PMID: 7668102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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