Article
Comparison of the prevalence of the poor metabolizer phenotype for CYP2D6 between 203 Hmong subjects and 280 white subjects residing in Minnesota.
Clinical pharmacology and therapeutics - 1 Jul 1995
Straka R J, Hansen S R, Walker P F
Abstract excerpt
Genetic polymorphism of the P450IID6 (CYP2D6) enzyme system can be an important component of the variability in response to drug therapy. Interpopulation differences in the prevalence of deficiencies of drug-metabolizing enzymes may be clinically important in the selection and dosage of drug ther...
Topics
- Adolescent
- Adult
- Aged
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Dextromethorphan
- Dextrorphan
- Ethnicity
- Female
- Humans
- Laos
- Male
- Middle Aged
- Minnesota
- Mixed Function Oxygenases
- Oxidation-Reduction
- Phenotype
- Polymorphism, Genetic
