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Article

Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations.

British journal of clinical pharmacology - 1 Oct 1991

Sohn D R, Shin S G, Park C W, Kusaka M, Chiba K, Ishizaki T

Abstract excerpt

We examined metoprolol oxidation capacity in 218 unrelated, healthy Korean subjects using the 8 h urinary metabolic ratio (MR) of metoprolol to alpha-hydroxymetoprolol after an oral dose of 100 mg metoprolol tartrate. The results were compared with those from 295 Japanese and 107 mainland Chinese whose metoprolol oxidation capacities were assessed in a similar manner. The frequency of occurrence of poor...

Topics

Adolescent
Adult
Asian People
China
Ethnicity
Female
Humans
Japan
Korea
Male
Metoprolol
Oxidation-Reduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1958447
DOI: 10.1111/j.1365-2125.1991.tb03939.x
PMCID: PMC1368614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1958447-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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