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Article

Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

Human molecular genetics - 1 Feb 1995

Risch A, Wallace D M, Bathers S, Sim E

Abstract excerpt

Bladder cancer is a common multifactorial disease and is known to be associated with occupational exposure to arylamines. Smoking is also a recognised contributory environmental cause. Occupational bladder cancer has previously been associated with slow acetylation by N-acetyltransferase (NAT) in humans in phenotyping studies, but more recently there has been some controversy regarding this issue. NAT is an...

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Source

Identifiers

PMID: 7757072
DOI: 10.1093/hmg/4.2.231

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.PMID 7757072Read ↗

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Genotyping of the polymorphic N-acetyltransferase (NAT2) and loss of heterozygosity in bladder cancer patients.Semantic proximity Read ↗

N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.Semantic proximity Read ↗

Association Between N-acetyltransferase 2 Polymorphism and Bladder Cancer Risk: Results From Studies of the Past Decade and a Meta-Analysis.Semantic proximity Read ↗

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Acetylation phenotypes and bladder cancer.Semantic proximity Read ↗

N-acetylation phenotype and genotype and risk of bladder cancer in benzidine-exposed workers.Semantic proximity Read ↗

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N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction.Semantic proximity Read ↗

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