Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

doi:10.1093/hmg/4.2.231

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Article

Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

Human molecular genetics - 1 Feb 1995

Risch A, Wallace D M, Bathers S, Sim E

Abstract excerpt

Bladder cancer is a common multifactorial disease and is known to be associated with occupational exposure to arylamines. Smoking is also a recognised contributory environmental cause. Occupational bladder cancer has previously been associated with slow acetylation by N-acetyltransferase (NAT) in humans in phenotyping studies, but more recently there has been some controversy regarding this issue. NAT is an...

Topics

Acetylation
Adult
Age Factors
Aged
Aged, 80 and over
Alleles
Arylamine N-Acetyltransferase
Carcinogens
England
Female
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Occupational Exposure

Phenotype

Risk Factors

Smoking

Source

Open in PubMed

Identifiers

PMID: 7757072
DOI: 10.1093/hmg/4.2.231

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7757072-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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