N-acetyltransferase activity--a susceptibility factor in human bladder carcinogenesis.

Abstract excerpt

A higher proportion of slow acetylator phenotypes has previously been found among bladder cancer patients. In the present study carried out among 77 male bladder cancer patients and 80 non-cancer controls, 59.74% of the patients and 35% of the controls were slow acetylator phenotypes (p < 0.01). The odds of developing bladder cancer was also observed to be significantly higher among smokers than non-smokers (p <...

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