Article
Activity of the beta 3 nicotinic receptor promoter is a marker of neuron fate determination during retina development.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1995
Matter J M, Matter-Sadzinski L, Ballivet M
Abstract excerpt
We have previously shown that transcription of the beta 3 nicotinic receptor gene within the chick CNS is regulated by a promoter 143 base pairs (bp) in length. Here, we demonstrate that in the developing visual system this promoter is active in a subset of retinal cells, the majority of which are ganglion cells. Because the beta 3 promoter is activated very early during retina development, it can provide a...
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