Article
The interaction of T4 endonuclease V E23Q mutant with thymine dimer- and tetrahydrofuran-containing DNA.
Journal of bacteriology - 1 Sept 1995
Latham K A, Manuel R C, Lloyd R S
Abstract excerpt
The interaction between endonuclease V, the cyclobutane pyrimidine dimer-specific N-glycosylase/abasic lyase from bacteriophage T4, and DNA was investigated by DNase I footprinting methods. The catalytically inactive mutant E23Q was found to interact with a smaller region of DNA at the abasic sit...
Topics
- Bacteriophage T4
- Base Sequence
- Binding Sites
- DNA
- Deoxyribonuclease (Pyrimidine Dimer)
- Endodeoxyribonucleases
- Furans
- Molecular Sequence Data
- Mutation
- Protein Binding
- Pyrimidine Dimers
- Sequence Analysis, DNA