Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies.

Neoplasia (New York, N.Y.) - 1 Jan 2000

Neville Phillippa J, Conti David V, Paris Pamela L, Levin Howard, Catalona William J, Suarez Brian K, Witte John S, Casey Graham

Abstract excerpt

The biologic aggressiveness of prostate tumors is an important indicator of prognosis. Chromosome 7q32-q33 was recently reported to show linkage to more aggressive prostate cancer, based on Gleason score, in a large sibling pair study. We report confirmation and narrowing of the linked region using finer-scale genotyping. We also report a high frequency of allelic imbalance (AI) defined within this locus in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genetic Linkage

Share to Microsatellite Repeats

Share to Neoplasm Staging

Share to Prostatic Neoplasms

Share to Radiation Hybrid Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 12192601
DOI: 10.1038/sj.neo.7900254
PMCID: PMC1564121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies.PMID 12192601Read ↗

Podocalyxin variants and risk of prostate cancer and tumor aggressiveness.Semantic proximity Read ↗

Prostate cancer aggressiveness locus on chromosome segment 19q12–q13.1 identified by linkage and allelic imbalance studiesSemantic proximity Read ↗

Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35.Semantic proximity Read ↗

Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics.Semantic proximity Read ↗

Genome-wide linkage scan for prostate cancer aggressiveness loci using families from the University of Michigan Prostate Cancer Genetics Project.Semantic proximity Read ↗

Genomewide scan for prostate cancer-aggressiveness loci.Semantic proximity Read ↗

The prostate cancer susceptibility variant rs2735839 near KLK3 gene is associated with aggressive prostate cancer and can stratify gleason score 7 patients.Semantic proximity Read ↗

Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression.Semantic proximity Read ↗

Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans.Semantic proximity Read ↗

Linkage of aggressive prostate cancer to chromosome 7q31-33 in German prostate cancer families.Semantic proximity Read ↗

Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases.Semantic proximity Read ↗

Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.