Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein.

Molecular biology of the cell - 1 May 1995

Winans K A, Hashimoto C

Abstract excerpt

Dorsoventral polarity of the Drosophila embryo is established by a signal transduction pathway in which the maternal transmembrane protein Toll appears to function as the receptor for a ventrally localized extracellular ligand. Certain dominant Toll alleles encode proteins that behave as partiall...

Topics

Alleles
Animals
Base Sequence
Cell Membrane
Cytoplasm
Drosophila
Drosophila Proteins
Female
Genes, Insect
Insect Hormones
Leucine
Ligands
Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Molecular Weight

RNA, Messenger

Receptors, Cell Surface

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 7663024
DOI: 10.1091/mbc.6.5.587
PMCID: PMC301217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7663024-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein.PMID 7663024Read ↗

Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.Semantic proximity Read ↗

Functional analysis of Toll-related genes in Drosophila.Semantic proximity Read ↗

The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway.Semantic proximity Read ↗

Toll homologue expression in the beetle tribolium suggests a different mode of dorsoventral patterning than in drosophila embryos.Semantic proximity Read ↗

The maternal nudel protein of Drosophila has two distinct roles important for embryogenesis.Semantic proximity Read ↗

Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.Semantic proximity Read ↗

The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.Semantic proximity Read ↗

DmMyD88 controls dorsoventral patterning of the Drosophila embryo.Semantic proximity Read ↗

Multiple isoforms of the Drosophila Spätzle protein are encoded by alternatively spliced maternal mRNAs in the precellular blastoderm embryo.Semantic proximity Read ↗

Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo.Semantic proximity Read ↗

The torpedo (DER) receptor tyrosine kinase is required at multiple times during Drosophila embryogenesis.Semantic proximity Read ↗

The polarity of the dorsoventral axis in the Drosophila embryo is defined by an extracellular signal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.