Article
Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein.
Molecular biology of the cell - 1 May 1995
Winans K A, Hashimoto C
Abstract excerpt
Dorsoventral polarity of the Drosophila embryo is established by a signal transduction pathway in which the maternal transmembrane protein Toll appears to function as the receptor for a ventrally localized extracellular ligand. Certain dominant Toll alleles encode proteins that behave as partially ligand-independent receptors, causing embryos containing these proteins to become ventralized. In extracts of embryos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
