Article
Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.
Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1991
Letsou A, Alexander S, Orth K, Wasserman S A
Abstract excerpt
Loss of maternal function of the tube gene disrupts a signaling pathway required for pattern formation in Drosophila, causing cells throughout the embryo to adopt the fate normally reserved for those at the dorsal surface. Here we demonstrate that tube mutations also have a zygotic effect on pupal morphology and that this phenotype is shared by mutations in Toll and pelle, two genes with apparent intracellular...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Walking
- Drosophila melanogaster
- Embryo, Nonmammalian
- Female
- Genes
- Molecular Sequence Data
- Phenotype
- Pupa