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Article

Toll homologue expression in the beetle tribolium suggests a different mode of dorsoventral patterning than in drosophila embryos.

Mechanisms of development - 1 May 1999

Maxton-KuchenmeisterMaxton-Kü, Handel K, Schmidt-Ott U, Roth S, JackleJäckle H

Abstract excerpt

The gene Toll (Tl) encodes a maternally supplied interleukin 1 receptor-related transmembrane protein, a key component required to establish dorsoventral polarity in the Drosophila embryo. We have isolated Tl homologs of a primitive dipteran, Clogmia albipunctata, and of the beetle Tribolium castaneum. Tribolium Tl protein (Tl) lacks sequences in the C-terminal portion of the cytoplasmic domains that are...

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PMID: 10381571
DOI: 10.1016/s0925-4773(99)00041-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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