Article
Age-related differences in regeneration of dystrophic (mdx) and normal muscle in the mouse.
Muscle & nerve - 1 Oct 1995
Pastoret C, Sebille A
Abstract excerpt
The mdx mouse, a genetic homologue of human Duchenne muscular dystrophy (DMD), has been attributed with a greater regenerative capacity of its skeletal muscles. Here, we have tested the hypothesis that muscles of mdx mice regenerate better than those of nondystrophic animals. We studied muscle regeneration resulting from a denervation-devascularization injury (DD) of extensor digitorum longus muscle (EDL) at 3...
Topics
- Aging
- Animals
- Male
- Mice
- Mice, Inbred C57BL
- Muscle Denervation
- Muscle Fibers, Skeletal
- Muscle, Skeletal
- Muscular Dystrophy, Animal
- Mutation
- Regeneration
- Time Factors