Dystrophy and myogenesis inmdx diaphragm muscle

Abstract excerpt

In order to determine why the diaphragm is more severely affected by progressive dystrophy than limb muscles in the mdx mouse, we examined how regional variations in diaphragm dystrophy, the measures of disease and repair, proliferation by committed myogenic cells, and the expression of mitogenic basic fibroblast growth factor (bFGF) could contribute to muscle-specific disease phenotypes. There were regional...