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Article

Genetic background affects properties of satellite cells and mdx phenotypes.

The American journal of pathology - 1 May 2010

Fukada So-ichiro, Morikawa Daisuke, Yamamoto Yukiko, Yoshida Tokuyuki, Sumie Noriaki, Yamaguchi Masahiko, Ito Takahito, Miyagoe-Suzuki Yuko, Takeda Shin'ichi, Tsujikawa Kazutake, Yamamoto Hiroshi

Abstract excerpt

Duchenne muscular dystrophy (DMD) is the most common lethal genetic disorder of children. The mdx (C57BL/10 background, C57BL/10-mdx) mouse is a widely used model of DMD, but the histopathological hallmarks of DMD, such as the smaller number of myofibers, accumulation of fat and fibrosis, and insufficient regeneration of myofibers, are not observed in adult C57BL/10-mdx except for in the diaphragm. In this study,...

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Identifiers

PMID: 20304955
DOI: 10.2353/ajpath.2010.090887
PMCID: PMC2861106

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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