Article
Phenotype of dystrophinopathy in old mdx mice.
The Anatomical record - 1 May 1995
Lefaucheur J P, Pastoret C, Sebille A
Abstract excerpt
BACKGROUND: Mdx mutant mice, like patients with Duchenne Muscular Dystrophy (DMD), lack dystrophin, a subsarcolemmal protein, that results in myofiber necrosis. However young mdx mice, in contrast to DMD children, exhibit a successful muscle regeneration and not an extensive fibrosis. METHODS: Ol...
Topics
- Aging
- Animals
- Female
- Fibrosis
- Hindlimb
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred mdx
- Muscle, Skeletal
- Muscle, Smooth
- Muscular Dystrophy, Animal
- Myocardium
- Phenotype