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Article

Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2007

Chamberlain Jeffrey S, Metzger Joseph, Reyes Morayma, Townsend DeWayne, Faulkner John A

Abstract excerpt

Duchenne muscular dystrophy (DMD) is the most common, lethal genetic disorder of children. A number of animal models of muscular dystrophy exist, but the most effective model for characterizing the structural and functional properties of dystrophin and therapeutic interventions has been the mdx mouse. Despite the approximately 20 years of investigations of the mdx mouse, the impact of the disease on the life span...

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Identifiers

PMID: 17360850
DOI: 10.1096/fj.06-7353com

Genes

DMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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