Article
Expression of cartilage-specific molecules is retained on long-term culture of human articular chondrocytes.
Journal of cell science - 1 May 1995
Kolettas E, Buluwela L, Bayliss M T, Muir H I
Abstract excerpt
Normal human adult articular chondrocytes were used to determine how the chondrocyte phenotype is modulated by culture conditions following long-term culture. We report here for the first time that human articular chondrocytes have a lifespan in the range of 34-37 population doublings. While chondrocytes cultured as monolayers displayed a fibroblastoid morphology and grew faster, those cultured as suspensions...
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