Article
Phenotypic characterization of human chondrocyte cell line C-20/A4: a comparison between monolayer and alginate suspension culture.
Cells, tissues, organs - 1 Jan 2004
Finger Florian, Schörle Cornelius, Soder Stephan, Zien Alexander, Goldring Mary B, Aigner Thomas
Abstract excerpt
DNA microarray analysis was used to investigate the molecular phenotype of one of the first human chondrocyte cell lines, C-20/A4, derived from juvenile costal chondrocytes by immortalization with origin-defective simian virus 40 large T antigen. Clontech Human Cancer Arrays 1.2 and quantitative PCR were used to examine gene expression profiles of C-20/A4 cells cultured in the presence of serum in monolayer and...
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