Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid phenotypic changes in passaged articular chondrocyte subpopulations.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Mar 2005

Darling Eric M, Athanasiou Kyriacos A

Abstract excerpt

Articular chondrocytes are often expanded in vitro and then used to assist in healing articular cartilage defects. We investigated the extent of dedifferentiation in monolayer-passaged, zonal articular chondrocytes by using quantitative, real-time PCR. The relative gene expressions for collagen type I and II, aggrecan, and superficial zone protein were analyzed for relevant passage numbers (P0-P4) to determine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aggrecans
Share to Alginates
Share to Cartilage, Articular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Glucuronic Acid

Share to Hexuronic Acids

Share to Lectins, C-Type

Share to Proteoglycans

Source

Identifiers

PMID: 15734258
DOI: 10.1016/j.orthres.2004.08.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid phenotypic changes in passaged articular chondrocyte subpopulations.PMID 15734258Read ↗

Cartilage tissue formation using redifferentiated passaged chondrocytes in vitro.Semantic proximity Read ↗

Retaining zonal chondrocyte phenotype by means of novel growth environments.Semantic proximity Read ↗

Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques.Semantic proximity Read ↗

Phenotypic re-expression of near quiescent chondrocytes: The effects of type II collagen and growth factors.Semantic proximity Read ↗

Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell cultureSemantic proximity Read ↗

Gene expression profiling of primary human articular chondrocytes in high-density micromasses reveals patterns of recovery, maintenance, re- and dedifferentiationSemantic proximity Read ↗

Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype.Semantic proximity Read ↗

Changes in chondrogenic phenotype and gene expression profiles associated with the in vitro expansion of human synovium-derived cells.Semantic proximity Read ↗

Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age.Semantic proximity Read ↗

Proteoglycan and Collagen Accumulation by Passaged Chondrocytes Can Be Enhanced Through Side-by-Side Culture with Primary ChondrocytesSemantic proximity Read ↗

Cartilage oligomeric matrix protein (COMP) and collagen IX are sensitive markers for the differentiation state of articular primary chondrocytes.Semantic proximity Read ↗

Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D culturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.