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Article

Development and characterization of a human articular cartilage-derived chondrocyte cell line that retains chondrocyte phenotype.

Journal of cellular physiology - 1 Mar 2010

Hoffman Bryan E, Newman-Tarr Tonie M, Gibbard Anna, Wang Shen, Hanning Charles, Pratta Michael A, Boyle Ryan J, Kumar Sanjay, Majumdar Manas K

Abstract excerpt

Chondrocytes, the only cell type present in articular cartilage, regulate tissue homeostasis by a fine balance of metabolism that includes both anabolic and catabolic activities. Therefore, the biology of chondrocytes is critical for understanding cartilage metabolism. One major limitation when studying primary chondrocytes in culture is their loss of phenotype. To overcome this hurdle, limited attempts have been...

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PMID: 20020445
DOI: 10.1002/jcp.21994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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