Article
In vitro T cell response to staphylococcal enterotoxin B superantigen in chronic plaque type psoriasis.
Acta dermato-venereologica - 1 May 1995
Bour H, Demidem A, Garrigue J L, Krasteva M, Schmitt D, Claudy A, Nicolas J F
Abstract excerpt
Recent studies have demonstrated the important role of CD4+ T cells in the pathophysiology of psoriasis. One of the current hypotheses is that triggering of the psoriatic inflammatory process could be secondary to CD4+ T cell activation by bacterial superantigens in the skin. In this study, IL-2-derived T cell lines were recovered from the blood and the skin of 4 patients with chronic plaque type psoriasis and of...
Topics
- Antigen-Presenting Cells
- CD4-Positive T-Lymphocytes
- Case-Control Studies
- Cell Division
- Cell Line
- Chronic Disease
- Dermatitis, Allergic Contact
- Enterotoxins
- HLA-D Antigens
- Humans
- Interleukin-2