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Article

Superantigenic properties of the group A streptococcal exotoxin SpeF (MF)

1 Dec 1994

Abstract excerpt

Streptococcal pyrogenic exotoxin F (SpeF), previously referred to as mitogenic factor, is a newly described potent mitogen produced by group A streptococci. To investigate whether this protein belongs to the family of microbial superantigens, we analyzed the cellular and molecular requirements for its presentation to T cells and compared it with the known streptococcal superantigen pyrogenic exotoxin A (SpeA) and...

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Identifiers

PMID: 7960098
DOI: 10.1128/iai.62.12.5227-5233.1994

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