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Article

Differential presentation of group A streptococcal superantigens by HLA class II DQ and DR alleles.

European journal of immunology - 1 Sept 2002

Norrby-Teglund Anna, Nepom Gerald T, Kotb Malak

Abstract excerpt

Superantigens have been implicated as pivotal mediators of severe invasive group A streptococcal (GAS) infections, by virtue of their potent immunostimulatory activity. HLA polymorphism has been suggested to influence the susceptibility to severe invasive GAS infection. Here we studied the influence of allelic and isotypic variation of HLA class II molecules on GAS superantigen-induced immune responses using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12207341
DOI: 10.1002/1521-4141(200209)32:9<2570::AID-IMMU2570>3.0.CO;2-E

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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