Article
Epidermal CD8+ T cells reactive with group A streptococcal antigens in chronic plaque psoriasis.
Experimental dermatology - 1 Aug 2002
Ovigne J-M, Baker B S, Davison S C, Powles A V, Fry L
Abstract excerpt
Chronic plaque psoriasis is a T cell mediated disease associated with group A streptococci (GAS). We have previously shown the presence of a psoriasis-specific dermal Th1 subset that recognizes GAS antigens. To assess whether GAS-reactive T cells are also present in lesional epidermis, fresh cell suspensions or T cell lines isolated from lesional epidermis of 33 psoriasis patients were stained for intracellular...
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