Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells

Abstract excerpt

Although clinical and laboratory evidence support roles for both staphylococcal infection and environmental allergens in the pathogenesis of atopic dermatitis, human studies have largely considered these variables independently. We sought to test the hypothesis that staphylococcal superantigen influences the allergen-specific T cell response. We first mapped a Der p 1 epitope and used HLA DRB1*1501 class II...

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• Share to Allergic Rhinitis and Sensitization
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