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Article

Analysis of the Short Consensus Repeats of Human Complement Factor B by Site-directed Mutagenesis

1 Aug 1995

Abstract excerpt

Human factor B is required for the initiation and propagation of the complement alternative pathway. It also participates in the amplification of the complement classical pathway. Alone, factor B is a zymogen with little known biochemical activity, but in the context of the alternative pathway convertases, the factor B serine protease is activated in a process that first involves the association with C3b and...

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PMID: 7649982
DOI: 10.1074/jbc.270.34.19716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the Short Consensus Repeats of Human Complement Factor B by Site-directed MutagenesisPMID 7649982Read ↗

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