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Article

Molecular evolution of three avian neurotrophin genes: implications for proregion functional constraints.

Journal of molecular evolution - 1 Sept 2003

Sehgal Ravinder N M, Lovette Irby J

Abstract excerpt

Neurotrophin proteins are essential for the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems. Recent studies have shown that the unprocessed proforms of the neurotrophins are preferential high-affinity ligands for p75NTR and potent inducers of p75(NTR)-mediated cell death. Here, we explore differences in the selective constraints acting on the proregions of the...

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Source

Identifiers

PMID: 14629043
DOI: 10.1007/s00239-003-2484-8

Genes

BDNF
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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