Article
HSV type 1 genome variants from persistently productive infections in Raji and BJAB cell lines.
Archives of virology - 1 Jan 1995
Klauck S M, Hampl W, Kleinschmidt A K
Abstract excerpt
We studied possible genomic changes occurring in herpes simplex virus type 1 (HSV-1) during long-term cell culture which served as a model system for persistence and latency studies as introduced earlier. Sixteen HSV-1 reisolates were isolated from persistently productive HSV-1 (strains F and AK)...
Topics
- Animals
- Base Sequence
- Chlorocebus aethiops
- DNA, Viral
- Genetic Variation
- Genome, Viral
- Herpesvirus 1, Human
- Humans
- Molecular Sequence Data
- Restriction Mapping
- Tumor Cells, Cultured
- Vero Cells
- Viral Plaque Assay
- Virus Latency