Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1.

doi:10.1016/0042-6822(90)90534-x

Article

Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1.

Virology - 1 Aug 1990

Barker D E, Roizman B

Abstract excerpt

We report the construction of herpes simplex virus 1 recombinants from which all or part of the coding sequences of four open reading frames have been deleted. In recombinants R7101 and R7108, the BamHI D' fragment containing the coding sequences of the dUTPase gene and the promoter-regulatory do...

Topics

Animals
Chromosome Deletion
Chromosome Mapping
Cloning, Molecular
DNA, Viral
Genes, Viral
Mutation
Plasmids
Rabbits
Repetitive Sequences, Nucleic Acid
Restriction Mapping
Simplexvirus
Skin
Transfection
Viral Plaque Assay
Virion

Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1.

Abstract excerpt

Topics

Discuss the evidence