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Article

Inversions with deletions and duplications.

Genetics - 1 May 1995

Gordon A J, Halliday J A

Abstract excerpt

Complex mutational events, including de novo inversion with deletion and duplication of sequence, have been observed but are difficult to model. We propose that nascent leading-strand misalignment upon the lagging-strand template during DNA replication can result in the inversion of sequence. The positioning of this misalignment and of the realignment of the leading strand back into the leading-strand template...

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Identifiers

PMID: 7635304
DOI: 10.1093/genetics/140.1.411
PMCID: PMC1206566

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Source receipt: pubmed, retrieved 7 Sept 2026.

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