Circular permutations in the molecular evolution of DNA methyltransferases.

Abstract excerpt

Circular permutations of genes during molecular evolution often are regarded as elusive, although a simple model can explain these rearrangements. The model assumes that first a gene duplication of the precursor gene occurs in such a way that both genes become fused in frame, leading to a tandem protein. After generation of a new start codon within the 5' part of the tandem gene and a stop at an equivalent...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA Modification Methylases
• Share to Evolution, Molecular
• Share to Gene Duplication