Article
Dual regulation of the Drosophila hsp26 promoter in vitro.
Nucleic acids research - 11 Jul 1995
Sandaltzopoulos R, Mitchelmore C, Bonte E, Wall G, Becker P B
Abstract excerpt
Efficient heat shock induction of Drosophila hsp26 gene transcription in vivo requires binding sites for heat shock factor (HSF) and GAGA factor (GAF) close to the TATA box (proximal elements) as well as 350 bp upstream of the start site of transcription (distal elements). We have evaluated the contribution of hsp26 promoter sequences to transcriptional activity in extracts from either heat shocked or unstressed...
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