Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats.

doi:10.1016/0022-2836(90)90075-W

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Article

Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats.

Journal of molecular biology - 20 Feb 1990

Glaser R L, Thomas G H, Siegfried E, Elgin S C, Lis J T

Abstract excerpt

We report here the analysis of the sequence requirements for the heat-induced expression of the Drosophila melanogaster hsp26 gene using germline transformation. Heat-induced expression is augmented fivefold by a homopurine/homopyrimidine region from -85 to -134 that is devoid of heat-shock elements but contains numerous (dC-dT).(dG-dA) repeats. Sequences within this interval have been shown to assume a nuclease...

Topics

Animals
Base Sequence
Cell Nucleus
DNA
Diethyl Pyrocarbonate
Drosophila
Embryo, Nonmammalian
Gene Expression Regulation
Genes
Heat-Shock Proteins
Hot Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Nucleic Acid Conformation

Oligonucleotide Probes

Plasmids

Promoter Regions, Genetic

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 2313697
DOI: 10.1016/0022-2836(90)90075-W

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2313697-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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