Article
[Kinetics of heat shock response upon disfunction of general transcription factor (HSF)].
Molekuliarnaia biologiia - 1 Jan 2000
Funikov S Iu, Garbuz D G, Zatsepina O G
Abstract excerpt
The heat shock transcription factor (HSF) is a universal activator of hsp gene expression in eukaryotes. A temperature sensitive Drosophila melanogaster strain (hsf4) with a mutation in the hsfgene was originally described as a strain lacking the transcription of hsp genes in response to heat shock. Our results demonstrated that physiological function of HSF4 is not fully abrogated after heat exposure and is able...
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