Article
[Dysfunction of E-cadherin due to mutation of beta-catenin in a scirrhous gastric cancer cell line].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1995
Kawanishi J, Kato J, Sasaki K, Fujii S, Watanabe N, Niitsu Y
Abstract excerpt
E-cadherin is a calcium dependent cell-cell adhesion molecule. In cancer tissue, detachment of the adhesion system is indispensable for invasion and metastasis of cancer cells. We have investigated mechanism of the dysfunction of E-cadherin-dependent cell-cell adhesion system in gastric carcinoma cells. Although the high expression of E-cadherin in a scirrhous gastric cancer cell line HSC-39, the function of...
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