[Dysfunction of E-cadherin due to mutation of beta-catenin in a scirrhous gastric cancer cell line].

Article

[Dysfunction of E-cadherin due to mutation of beta-catenin in a scirrhous gastric cancer cell line].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1995

Kawanishi J, Kato J, Sasaki K, Fujii S, Watanabe N, Niitsu Y

Abstract excerpt

E-cadherin is a calcium dependent cell-cell adhesion molecule. In cancer tissue, detachment of the adhesion system is indispensable for invasion and metastasis of cancer cells. We have investigated mechanism of the dysfunction of E-cadherin-dependent cell-cell adhesion system in gastric carcinoma...

Topics

Adenocarcinoma, Scirrhous
Cadherins
Cytoskeletal Proteins
Gene Deletion
Humans
Mutation
Stomach Neoplasms
Trans-Activators
Tumor Cells, Cultured
beta Catenin

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