Article
[Genetic characteristics of scirrhous gastric carcinomas].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Oct 1994
Yokozaki H, Kuniyasu H, Yasui W, Tahara E
Abstract excerpt
Genetic characteristics of scirrhous gastric carcinomas are overviewed. Scirrhous carcinomas of the stomach frequently show amplification of c-met and K-sam oncogenes as well as overexpression of 6.0 kb c-met abnormal transcript. For the formation of productive fibrosis and the diffuse infiltrative growth pattern of this malignancy, the essential factors would be not only the loss of cell adhesion molecule...
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