Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MacMARCKS mutation blocks macrophage phagocytosis of zymosan.

The Journal of biological chemistry - 28 Jul 1995

Zhu Z, Bao Z, Li J

Abstract excerpt

A major protein kinase C substrate, MacMARCKS (F52, MPR), was examined for its role in phagocytosis. In macrophage-phagocytosing zymosan particles, MacMARCKS was concentrated around nascent phagosomes as detected by immunofluorescent microscopy. The effector domain of MacMARCKS contains the phosphorylation sites, a calmodulin binding site, as well as a putative actin binding site. Stable J774 macrophage cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules
Share to Cell Line
Share to Macrophages

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Mutation

Share to Protein Kinase C

Share to Proteins

Share to Receptors, LDL

Source

Identifiers

PMID: 7629059
DOI: 10.1074/jbc.270.30.17652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MacMARCKS mutation blocks macrophage phagocytosis of zymosan.PMID 7629059Read ↗

Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin.Semantic proximity Read ↗

Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis.Semantic proximity Read ↗

Macrophage-enriched myristoylated alanine-rich C kinase substrate and its phosphorylation is required for the phorbol ester-stimulated diffusion of beta 2 integrin molecules.Semantic proximity Read ↗

Proteomic analysis reveals a role for protein kinase C-alpha in phagosome maturation.Semantic proximity Read ↗

Distinct cellular functions of MK2.Semantic proximity Read ↗

PhosphoMARCKS drives motility of mouse melanoma cells.Semantic proximity Read ↗

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosisSemantic proximity Read ↗

The role of mannose receptor during experimental leishmaniasisSemantic proximity Read ↗

Signal sequence within Fc gamma RIIA controls calcium wave propagation patterns: apparent role in phagolysosome fusion.Semantic proximity Read ↗

Fc receptor-mediated phagocytosis requires CDC42 and Rac1.Semantic proximity Read ↗

Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages.Semantic proximity Read ↗

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.