Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin.

The Journal of biological chemistry - 31 May 1996

Li J, Zhu Z, Bao Z

Abstract excerpt

The cellular function of the MARCKS family of protein kinase C substrates is unknown. In this report, we present evidence that indicates a role for MacMARCKS, a member of the MARCKS family, in the integrin-dependent signal transduction pathways in macrophages. Using a dominant negative mutant of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Line
Share to Cell Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Phosphorylation

Share to Proteins

Source

Identifiers

PMID: 8662782
DOI: 10.1074/jbc.271.22.12985

Genes

MARCKS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8662782-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillin.PMID 8662782Read ↗

MacMARCKS mutation blocks macrophage phagocytosis of zymosan.Semantic proximity Read ↗

MARCKS regulates membrane ruffling and cell spreading.Semantic proximity Read ↗

Macrophage-enriched myristoylated alanine-rich C kinase substrate and its phosphorylation is required for the phorbol ester-stimulated diffusion of beta 2 integrin molecules.Semantic proximity Read ↗

Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism.Semantic proximity Read ↗

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.Semantic proximity Read ↗

Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading.Semantic proximity Read ↗

MERTK Coordinates Efferocytosis by Regulating Integrin Localization and ActivationSemantic proximity Read ↗

Molecular cell biology of complement membrane attackSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.