Evidence for an evolutionary relationship among type-II restriction endonucleases.

doi:10.1016/0378-1119(95)00181-5

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Article

Evidence for an evolutionary relationship among type-II restriction endonucleases.

Gene - 4 Jul 1995

Jeltsch A, Kröger M, Pingoud A

Abstract excerpt

Type-II restriction-modification (R-M) systems comprise two enzymes, a DNA methyltransferase (MTase) and a restriction endonuclease (ENase), each of which specifically interact with the same 4-8 bp sequence. All type-II MTases share several amino acid (aa) sequence motifs, which makes an evolutio...

Topics

Amino Acid Sequence
Bacteria
Base Composition
Biological Evolution
Deoxyribonucleases, Type II Site-Specific
Genotype
Monte Carlo Method
Phenotype
Phylogeny
Sequence Homology, Amino Acid
Substrate Specificity

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