Article
Diversity of DNA methyltransferases that recognize asymmetric target sequences.
Critical reviews in biochemistry and molecular biology - 1 Apr 2010
Madhusoodanan Urulangodi Kunhiraman, Rao Desirazu N
Abstract excerpt
DNA methyltransferases (MTases) are a group of enzymes that catalyze the methyl group transfer from S-adenosyl-L-methionine in a sequence-specific manner. Orthodox Type II DNA MTases usually recognize palindromic DNA sequences and add a methyl group to the target base (either adenine or cytosine) on both strands. However, there are a number of MTases that recognize asymmetric target sequences and differ in their...
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