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Article

Individual- and population-based diversity in restriction-modification systems.

Bulletin of mathematical biology - 1 Jul 2000

Pagie L, Hogeweg P

Abstract excerpt

Restriction-modification (RM) systems are cognate gene complexes that code for an endonuclease and a methylase. They are often thought to have developed in bacteria as protection against invading genetic material, e.g., phage DNA. The high diversity of RM systems, as observed in nature, is often ascribed to the coevolution of RM systems (which 'invent' novel types) and phages. However, the extent to which phages...

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Identifiers

PMID: 10938631
DOI: 10.1006/bulm.2000.0177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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