Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations that confer de novo activity upon a maintenance methyltransferase.

Journal of molecular biology - 20 Sept 1991

Kelleher J E, Daniel A S, Murray N E

Abstract excerpt

DNA methyltransferases are not only sequence specific in their action, but they also differentiate between the alternative methylation states of a target site. Some methyltransferases are equally active on either unmethylated or hemimethylated DNA and consequently function as de novo methyltransferases. Others are specific for hemimethylated target sequences, consistent with the postulated role of a maintenance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage lambda
Share to Chromosomes, Bacterial
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Methylation

Share to Mutation

Share to Phenotype

Share to Viral Proteins

Source

Identifiers

PMID: 1833555
DOI: 10.1016/0022-2836(91)80064-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations that confer de novo activity upon a maintenance methyltransferase.PMID 1833555Read ↗

Epigenetic regulation in prokaryotes: transcriptional and phenotypic outcomes of DNA methyltransferase activity.Semantic proximity Read ↗

Maintenance forced by a restriction-modification system can be modulated by a region in its modification enzyme not essential for methyltransferase activity.Semantic proximity Read ↗

Role of DNA methyltransferases in epigenetic regulation in bacteria.Semantic proximity Read ↗

Target recognition by EcoKI: the recognition domain is robust and restriction-deficiency commonly results from the proteolytic control of enzyme activity.Semantic proximity Read ↗

DNA methylation and mutator genes in Escherichia coli K-12.Semantic proximity Read ↗

The impact of DNA methylation in AlphaproteobacteriaSemantic proximity Read ↗

Diversification of the restriction–modification system of <i>Streptococcus pyogenes</i> through its acquisition of mobile elementsSemantic proximity Read ↗

Diversity of DNA methyltransferases that recognize asymmetric target sequences.Semantic proximity Read ↗

DNA methyltransferase enhanced <i>Fusobacterium nucleatum</i> geneticsSemantic proximity Read ↗

Is modification sufficient to protect a bacterial chromosome from a resident restriction endonuclease?Semantic proximity Read ↗

Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification SystemsSemantic proximity Read ↗

EcoBLMcrX, a classical modification-dependent restriction enzyme in Escherichia coli B: Characterization in vivo and in vitro with a new approach to cleavage site determination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.