Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular evolution of DNA-(cytosine-N4) methyltransferases: evidence for their polyphyletic origin.

Nucleic acids research - 15 Nov 1999

Bujnicki J M, Radlinska M

Abstract excerpt

DNA N4-cytosine methyltransferases (N4mC MTases) are a family of S-adenosyl-L-methionine (AdoMet)-dependent MTases. Members of this family were previously found to share nine conserved sequence motifs, but the evolutionary basis of these similarities has never been studied in detail. We performed phylogenetic analysis of 37 known and potential new family members from the multiple sequence alignment using distance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacteria
Share to DNA-Cytosine Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Phylogeny

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 10536161
DOI: 10.1093/nar/27.22.4501
PMCID: PMC148735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular evolution of DNA-(cytosine-N4) methyltransferases: evidence for their polyphyletic origin.PMID 10536161Read ↗

The impact of DNA methylation in AlphaproteobacteriaSemantic proximity Read ↗

Diversity of DNA methyltransferases that recognize asymmetric target sequences.Semantic proximity Read ↗

Movement of DNA sequence recognition domains between non-orthologous proteins.Semantic proximity Read ↗

Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales.Semantic proximity Read ↗

Novel m4C modification in type I restriction-modification systems.Semantic proximity Read ↗

Impacts of <i>Mycoplasma agalactiae</i> restriction-modification systems on pan-epigenome dynamics and genome plasticitySemantic proximity Read ↗

Epigenetic regulation in prokaryotes: transcriptional and phenotypic outcomes of DNA methyltransferase activity.Semantic proximity Read ↗

Role of DNA methyltransferases in epigenetic regulation in bacteria.Semantic proximity Read ↗

MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing.Semantic proximity Read ↗

Genome comparison and context analysis reveals putative mobile forms of restriction-modification systems and related rearrangements.Semantic proximity Read ↗

Circular permutations in the molecular evolution of DNA methyltransferases.Semantic proximity Read ↗

Methylome Diversification through Changes in DNA Methyltransferase Sequence SpecificitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.