Genotyping of DNA using sequence-specific methyltransferases followed by immunochemical detection.

Abstract excerpt

Modern molecular genetics relies on the ability to map the positions of genes on chromosomes, relative to known DNA markers. The first such DNA markers described were Restriction Fragment Length Polymorphisms, but any restriction endonuclease used for RFLP mapping is just one member of a restriction-modification pair. For each restriction endonuclease, there is a companion methyltransferase (MTase) that has the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophages
• Share to DNA Fingerprinting
• Share to Globins