Article
Three novel mutations in the RET proto-oncogene.
Journal of molecular medicine (Berlin, Germany) - 1 Oct 2001
Kalinin V N, Amosenko F A, Shabanov M A, Lubchenko L N, Hosch S B, Garkavtseva R F, Izbicki J R
Abstract excerpt
Medullary thyroid carcinoma (MTC) occurs as a sporadic tumor or in connection with inherited cancer syndromes of multiple endocrine neoplasia type 2 and familial MTC. Missense RET proto-oncogene mutations and small in-frame deletions are found in most of the cases. In a significant amount of spor...
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